Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants.

Hongbo Liu, Amin Abedini, Eunji Ha, Ziyuan Ma, Xin Sheng, Bernhard Dumoulin, Chengxiang Qiu,Tamas Aranyi, Shen Li, Nicole Dittrich, Hua-Chang Chen, Ran Tao, Der-Cherng Tarng, Feng-Jen Hsieh,Shih-Ann Chen, Shun-Fa Yang, Mei-Yueh Lee, Pui-Yan Kwok, Jer-Yuarn Wu, Chien-Hsiun Chen,Atlas Khan, Nita A. Limdi, Wei-Qi Wei, Theresa L. Walunas, Elizabeth W. Karlson, Eimear E. Kenny,Yuan Luo, Leah Kottyan, John J. Connolly, Gail P. Jarvik, Chunhua Weng, Ning Shang, Joanne B. Cole,Josep M. Mercader, Ravi Mandla, Timothy D. Majarian, Jose C. Florez, Mary E. Haas, Luca A. Lotta,Regeneron Genetics Center, GHS-RGC DiscovEHR Collaboration, Theodore G. Drivas,Penn Medicine BioBank, Ha My T. Vy, Girish N. Nadkarni, Laura K. Wiley, Melissa P. Wilson,Christopher R. Gignoux, Humaira Rasheed, Laurent F. Thomas, Bjørn Olav Åsvold, Ben M. Brumpton,Stein I. Hallan, Kristian Hveem, Jie Zheng, Jacklyn N. Hellwege, Matthew Zawistowski, Sebastian Zöllner,Nora Franceschini, Hailong Hu, Jianfu Zhou, Krzysztof Kiryluk, Marylyn D. Ritchie,Matthew Palmer, Todd L. Edwards, Benjamin F. Voight, Adriana M. Hung, Katalin Susztak

Science 2025, 387(6734)