Developing mouse kidney scRNA-seq and snATAC-seq studies (Miao, Z. et al., Nature Communications, 2021):
Miao, Z. et al. Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets. Nature Communications (2021).
Human kidney snATAC-seq, cell fraction eQTL and cell type interaction eQTL studies (Sheng, X. et al., bioRxiv, 2020):
Sheng, X. et al. Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments. bioRxiv (2020).
Disease mouse kidney scRNA-seq study (Dhillon, P. et al., Cell Metabolism, 2020):
Dhillon, P. et al. The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation. Cell Metabolism (2020).
Human whole blood mQTL study (Sheng, X. et al., Proceedings of the National Academy of Sciences, 2020):
Sheng, X. et al. Systematic integrated analysis of genetic and epigenetic variation in diabetic kidney disease. Proceedings of the National Academy of Sciences (2020).
Summary Statistics data for mQTL and MWAS:
The clinical records for CRIC samples
Bulk eQTL study (Qiu, C. et al., Nature Medicine, 2018):
Qiu, C. et al. Renal compartment–specific genetic variation analyses identify new pathways in chronic kidney disease. Nature medicine 24, 1721 (2018).
Healthy mouse kidney single cell RNA-seq study (Park, J. et al., Science, 2018):
Park, J. et al. Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease. Science (2018).